Microsoft Intune supports management of virtual machines (VMs) in several ways, including:

1. Azure VMs : Microsoft Intune can manage VMs that are hosted in the Azure cloud. This includes managing software updates, enforcing compliance policies, and deploying software to Azure VMs.

2. VMs in on-premises data centers : Microsoft Intune can manage VMs that are hosted in on-premises data centers. This includes managing software updates, enforcing compliance policies, and deploying software to on-premises VMs.

3. Virtual desktop infrastructure (VDI) : Microsoft Intune can manage VDI environments, including virtual desktops and applications hosted on Remote Desktop Services (RDS) or Windows Virtual Desktop (WVD).
4. Third-party virtualization solutions : Microsoft Intune supports management of virtual machines hosted on third-party virtualization solutions, including VMware and Citrix.

In all of these scenarios, Microsoft Intune can be used to manage and secure virtual machines just like physical devices. This includes deploying software updates, enforcing compliance policies, configuring security settings, and managing applications.

Microsoft Intune also integrates with other Microsoft technologies, such as System Center Configuration Manager (SCCM) and Azure Automation, to provide a comprehensive solution for managing VMs and other types of devices.