MIS is a very crucial resource for an organization. MIS failures can create a big negative impact on the company that has designed it. MIS failure is very expensive for the company in terms of money wastage, time wastage, resource wastage, etc. So, the organization needs to identify the root causes of MIS failure and be alert to these concerns during the development of MIS.

Followings are the main root causes of MIS failure may arise due to followings :

Incomplete analysis : incomplete analysis is the biggest cause of system failure. An incomplete analysis is due to some common reasons like problem identification is not properly defined, key requirements and constraints are not properly understood and identify at the early stages of the MIS design and development process.

Lack of management involvement : Lack of management involvement have long-lasting consequences and can impact an entire system. Many executives who are not personally involved in MIS system design would most likely is a cause of system failure.
The accent of the computerized system : if someone doesn't understand the procedures and its need for handling input and output system, hardware and its usage, and application and its impacts; makes the biggest cause of MIS failure.

Concentration on low-level data processing : Information must be easily accessible and understood.

Lack of management knowledge of ICT systems and capabilities : the implementation and use of ICT to enhance and encourage knowledge management. Managers know what they want from the system but don't understand the technology

Lack of teamwork : During MIS design, An ICT director must organize the divisions of accounts, marketing, distribution, etc. to help everybody understand the benefits of the system.
Lack of professional standards –All systems require simple documentation that can be understood by all users.